Alcohol and E. G Cocaine Rf Essay

TLC is an analytical tool widely used because of its simplicity. Its performed on the analytical scale , meaning the monitoring of the progress of reaction or on the preparative scale to purify small amount of compounds. .A chromatography is used to separate mixtures of substances into their own components. This usually contains a stationary phase (which is a solid or liquid supported on a substance) and the mobile phase (which is a liquid or a gas). Usually the mobile phase flows through the stationary phase and then carries the components. Different components travel at different rates. The 3 mixturees that were used in the experiment were cocaine, methanol and benzyl.

Cocaine is an alkaloid. The chemical name for cocaine is benzoylmethyl-ecogine. The coicaine chemical structure consists three parts: lipophiic group, hydrophililic group and an aliphatic group. (Sabino, 2011)

Benzoylecogine is a topical analgesic and its the main metabolite of cocaine. Its the corresponding or carboxylic acid of coicaine and its a methyl ester (Evans, 1979)
Methanol is a alcohol compound, which contains three hydrogen atoms and one carbon atoms which makes the methyl group (CH3).

Results
Figure1 Data and Calculations.
Standard Solutions
Solvent front (cm)
Spot Distance (cm)
Rf Value
Coicaine
9
6.3
0.7
Benzoylecogonine
9
3.4
0.3
Metahnol
9
-
-

Rf Calculation
Rf Values = Distance from the baseline travelled by the solution

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