In 1859, people were inhaling amyl nitrate vapor. It was not until 1867 that a Scottish physician used amyl nitrate for medical use in patients. Amyl nitrate was prescribed and used to treat and provide relief from angina, a type of severe chest pain. In 1937, amyl nitrate poppers were considered as a prescription drug in the United States. This remained until the Food and Drug Administration removed amyl nitrate poppers as a required prescription medicine. Pharmacies and drug manufacturers noticed that many young, healthy men were buying amyl nitrate poppers in the late 1960s. So, the Food and Drug Administration reinstated amyl nitrate as a required prescription medicine. A secret amyl nitrate market had formed soon after, for people looking
