Fifth Edition
Talaro
Chapter
1
Microbiology
• The study of of organisms too small to be seen without magnification
– bacteria
– viruses
– fungi
– protozoa
– helminths (worms)
– algae
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3
Branches of study within microbiology • Immunology
• Public health microbiology & epidemiology
• Food, dairy and aquatic microbiology
• Biotechnology
• Genetic engineering & recombinant DNA technology 4
Microbes are involved in
• nutrient production & energy flow
• decomposition
• production of foods, drugs & vaccines
• bioremediation
• causing disease
5
Impact of pathogens
• Nearly 2,000 different microbes cause diseases • 10 B infections/year worldwide
• 13 M deaths from infections/year worldwide
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7
8
Characteristics of microbes
9
10
Antonie van Leeuwenhoek
• First to observe living microbes • his singlelens magnified up to 300X
(16321723)
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12
Spontaneous generation
Early belief that some forms of life could arise from vital forces present in nonliving or decomposing matter.
(flies from manure, etc)
14
Louis Pasteur
• Showed microbes caused fermentation & spoilage
• Disproved spontaneous generation of m.o.
• Developed aseptic techniques. • Developed a rabies vaccine.
(18221895)
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16
Germ theory of disease
Many diseases are caused by the growth of microbes in the body and not by sins, bad character, or poverty, etc.
Robert Koch
• Established a sequence of experimental steps to show that a specific m.o. causes a particular disease. • Developed pure culture methods. • Identified cause of anthrax, TB, & cholera.
(18431910)
18
Taxonomy system for organizing, classifying & naming living things
• Domain Archaea, Bacteria &
Eukarya