Chronic Gout Research Paper

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Pages: 3
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William Braden Smith
Nutrition 423
Professor: Dr. Sarah Colby
Topic Paper
Due: 1/26/15
Dietary Management of Chronic Gout

Gout is a specific type of arthritis that affects approximately 1% of the Caucasian population and is caused by the accumulation of uric acid in various joints in the body. Gout may be chronic and reoccur frequently or may also be acute and occur infrequently. The metabolic process of purine metabolism, primarily purines derived from animal meat or from proteins endogenous to the human body, is responsible for gout. In this catabolic process, the purines are broken down into urate, and should be further metabolized to allantoin by uricase, which is quite soluble in the bloodstream and may be excreted via the urinary tract …show more content…
Chronic gout is treated with a wide variety of drugs, but is also treated by making lifestyle modifications. Individuals who have a body mass index larger than 28 kilograms per meter squared are encouraged to lose weight. Patients are also encouraged to decrease their amount of meats and to increase their consumption of low-fat dairy foods and beverages. Additionally, patients with an alcohol intake of over 50 grams per day are encouraged to cease drinking or reduce the amount of alcohol in the diet. (Adebajo, 2009). Recent findings have indicated how effective reducing meats derived from animals in the daily diet can be. In Zhang et al, the association between purine consumption from animal and plant sources and the incidence of gout was examined for 633 individuals that had been diagnosed with chronic gout. The participants in the lowest quintile of animal meat consumption experienced gout attacks four times less frequently than those in the highest quintile of animal meat consumption. Analysis of the purines from plant sources showed that those who were in the lowest quintile had only slightly less gout attacks than those in the highest quintile of purine consumption from plant sources. Thus, the results suggest that the avoidance of purines from plant foods have little effect on gout outbreaks, while the avoidance of purines from animal origins can make a significant difference in the frequency of gout attacks in individuals diagnosed with chronic gout (Zhang et al,
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