Clindamycin And Methicillin: A Case Study

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With the rising incidence of MRSA, selecting the optimal antibiotics is critical to provide an effective therapy. Since the process of identifying the specific causative organism can take up to several days, an intravenous treatment that provides an adequate coverage of possible pathogens is initiated to prevent the spread of the bacteria. According to Hockenberry (2013c), clindamycin and nafcillin are most commonly used to treat S. aureus (p. 1080). Over the years, there has been a gradual emergence of strains resistant to penicillin and methicillin. Therefore, nafcillin, which is an antibiotic in the penicillin class, would not be as effective if the identified pathogen is resistant to penicillin. Even though clindamycin works against some …show more content…
It was discontinued once the causative agent was identified to be methicillin-susceptible Staphylococcus aureus (MSSA). Instead of receiving clindamycin or nafcilin, cefazolin, a first-generation cephalosporin, was administered for the next two days. However, my patient complained about irritation and tenderness at his right antecubital IV site. The attending physician discontinued and prescribed ibuprofen, an oral antibiotics, upon patient’s request. Bacitracin was also ordered as a PRN medication to treat his infection, but it is not one of the drugs to treat osteomyelitis based on the literature. The action mechanism of bacitracin is similar to vancomycin and cefazolin; they inhibit bacteria from synthesizing the cell wall and cause cell …show more content…
(2013c), magnetic resonance imaging is reported to be the most sensitive diagnostic radiologic tool for identifying and diagnosing osteomyelitis (p. 1080). This is a noninvasive diagnostic scanning technique that incorporates a magnetic field with the use of radio frequency pulses. MRI is commonly used to investigate the anatomy of the body, such as the head, chest, abdomen, bones and joints, and spine. This imaging technique has the advantages of not posing any health risk and providing better contrast between normal and abnormal tissues (Pagana and Pagana, 2014). The severity of the infected area can be identified with the high-quality image of the specific tissue or joint that may reveal the presence of an involucrum around the periosteal new bone or a formation of blood abscess. My patient had an acute post-traumatic lateral right ankle pain following a basketball injury and a trampoline accident respectively 14 days and 3 days ago. His MRI results revealed a thin nonspecific subperiosteal fluid collection around the anterolateral aspect of the lateral malleolus at the level of distal fibular metaphysis with no evidence of ankle effusion or
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