Coffee is slightly acidic (pH 5.0–5.1[1]) and can have a stimulating effect on humans because of its caffeine content. It is one of the most popular drinks in the world.[2] It can be prepared and presented in a variety of ways. The effect of coffee on human health has been a subject of many studies; however, results have varied in terms of coffee's relative benefit.[3] The majority of recent research suggests that moderate coffee consumption is benign or mildly beneficial in healthy adults. However, coffee can worsen the symptoms of conditions such as anxiety, largely due to the caffeine and diterpenes[citation needed] it contains.
Coffee cultivation first took place in southern Arabia;[4] the earliest credible evidence of coffee-drinking appears in the middle of the 15th century in the Sufi shrines of Yemen.[4] In East Africa and