I have to know how specific cancers effect the body, as well as, how current patient comorbidities play into their outcome. Recently, I cared for a patient with Acute Myeloid Leukemia (AML). He was admitted for a low platelet and hemoglobin count. During dayshift he received two units of blood. At the start of my shift, I had to administer a unit of platelets. He responded fine during the infusion without a reaction. About 30 minutes after the platelet infusion, I returned to his room to administer medications. I found the patient lying in his bed with rigors. I obtained a set of vital signs. His temperature was 101, pulse 125, respirations 24, blood pressure 80/48, and oxygen saturation of 79%. My first instinct was he was reacting to the platelets. However, my gut told me this was the beginning of sepsis. His white count was less than one. I called a rapid response and he was transferred to an intensive care unit. I found out the days later he was septic. Due to quick action, the patient had a good outcome and was able to transfer back to our floor