Name: MAI QUANG MINH
ID: 1400134
Essay for Dermatomyositis
1. Introduction:
Dermatomyositis is one of the most common seen types of idiopathic inflammatory myopathy. The disease is assuredly the consequence of the autoimmune process which characterized by muscle weakness, distinctive skin rash on face, chest, nails, elbow. This systemic disease affects not only the skin and the muscle but also others: joints, esophagus, lung, ect. Adults and children, men or women of any ages can also be affected with this disease. The complete treatment for this disease hasn’t been found yet, but the recent method to improve for this condition is help the patients regain the muscle strength and reduce complications.
2. Pathogenesis:
3. Signs and symptoms:…show more content… Malignancy: All patients with dermatomyositis should undergo a thorough medical history and careful physical examination.
4. Diagnosis:
The clinical criteria: clinically compatible manifestation found in patients is the great belief for the diagnosis.
Laboratory:
Dermatomyositis is confirmed by analyzing of serum muscle enzyme, EMG findings and muscle biopsy.
The most sensitive enzyme is Creatinine kinase(CK), CK is always elevated in patients with active dermatomyositis.
Needle EMG performs myopathic potentials, measures the speed and strength of signals traveling between two or more points. Its results reveals the nerve dysfunction, muscle dysfunction, or signal transduction problems between nerve and muscle.
Muscle biopsy is sensitive and specific test for establishing the diagnosis for inflammatory myopathy and for excluding other neuromuscular diseases. Differential diagnosis of dermatomyositis: Muscle diseases: Acute myopathy – Acute viral or bacterial infections Familial idiopathic…show more content… It is the most prevalent presentation of inflammatory muscle disease in children. Whereas, this disease also occurs in adults. Dermatomyositis in adult is regularly pertaining to malignancy, thus, a circumspect evaluation of each patient should be part of their initial and follow-up assessments. The existence of esophageal, pulmonary, and cardiac diseases needs evaluating carefully. Calcinosis is commonly observed in children than adults. Early and appropriately aggressive therapy can prevent effectively the complications. n. Corticosteroids, immunosuppressive drugs, biologic agents or even immunoglobulin are efficient weapons for the muscle diseases of dermatomyositis. Skin disease is controlled with sun protection, topical corticosteroids, or immunoglobulin. Good prognosis is surely for these patients without
