E01 Assignment 1

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Pages: 2
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Adam Peery
William Kistler
BIOL 3611 – E01- Group 30
Homework 1

1. A phospholipid bilayer without proteins would lose its cell signaling functions, lose its ability to transport the molecules that would normally be transported or channeled with a trans-membrane protein, and lose its enzyme metabolism functions. An example of a membrane bound protein that is a metabolism enzyme is ATP synthase, which phosphorylates ADP to ATP during cellular respiration. An example of a trans-membrane protein that functions as transporter would be the Na+/K+ Pump, which balances these ions to maintain homeostasis. Cell signaling proteins that are bound to a cell membrane respond to ligand signals with conformational changes. Neurotransmitters activate protein receptors in the membrane to induce brain activity.
2. The Phospholipid bilayer is made up of phospholipids, which have a hydrophilic head and a hydrophobic tail. The presence of increased C=C (carbon double bonds) make a lipid more fluid. The length of the lipid chains also determines fluidity. Less carbon atoms or a shorter lipid chain equates to a more fluid membrane. The increased presence of cholesterol helps to regulate the membrane fluidity in colder temperatures.
3. A.

B.

C. 4. …show more content…
Membrane A was estimated to have a Tm of 70° C because it has a dense body of saturated fatty acids (16:0) with some cholesterol making it a less fluid membrane. Membrane B was estimated to have a Tm of 45° C because it has a mixture of short saturated fatty acids (14:0) and unsaturated fatty acids (16:3) which makes it semi fluid with a lower Tm. Membrane C had an estimated Tm of 10° C because it was made up with oleate and linoleate, lipids which have a very low expected Tm. These were all estimated based on the values in Figure 7-13, by adding the different types of hydrocarbon chains and finding the mean temperatures from the
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