Do we have to include the hormones that effect it too?
2. How might over-secretion of insulin, which results in an exaggerated response to rising hypoglycemia be related to insulin resistance? In many people with type 2 diabetes who have insulin resistance, the lipolytic effects of epinephrine outweigh the effects of insulin on adipose tissue. Plasma free fatty acids increase in response to hypoglycemia in type 2 diabetes but do not in type 1 diabetes. Epinephrine secretion during hypoglycemia may therefore have a greater protective effect in insulin-resistant patients by promoting metabolic substrate release rather than storage. Epinephrine also stimulates release of glucose from the kidney, and, in people who have a deficient