Gastric Polypectomy Lab Report

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We observed no significant changes of gastrin level in the blood in response to test meal in patients within one year after polypectomy in the absence of disease recurrence.
Thus, significant hypergastrinemia develops in response to test meal in patients with gastric polyposis without the disease recurrence, and one year after surgery gastrin level reaches close to that of healthy individuals.
Gastrin level in the blood increased within 15 minutes after test meal in patients with gastric polyposis and the disease recurrence before the polypectomy performance, reaching a valid value of 281.6+37.0 pg/ml after 30 minutes, which is much higher than gastrin concentration in the control group at the same moment (see Table 5).
Test meal within one …show more content…
In the context of the investigation data of gastrin level in patients within one year after polypectomy, it was interesting to estimate the level of gastrinemia after test meal in patients within one year after gastrectomy for polyposis (see Table 6). Thus, gastrectomy in patients with polyposis reduces the basal level of gastrin by 1.8 times as compared to control level. And, standard test meal causes a slight increase in gastrin level in the blood within one year after the gastric resection. Even the highest level of gastrin did not reach the basal level in healthy individuals at this moment (Table …show more content…
This is confirmed by a more pronounced hypergastrinemia before the polypectomy in patients, who were diagnosed with a recurrence within one year after the surgery. This indicator can serve as an additional sign of polyp recurrence since gastrinemiya in recurrence is more than twice higher than that seen in patients without identified polyposis recurrence within one year after polypectomy.
Conclusion
Despite the fact, that polypectomy decreases the gastrin concentration in the blood (which indicates a decrease in the risk of the disease recurrence), yet gastric resection should be considered the most radical surgery for multiple polyps. After this surgery, even the test meal does not increase the level of gastrin and it stays equal to its basal level in healthy individuals.
Once again it should be noted that polyps are most frequently formed in the pyloric antrum that can be confirmed by a higher content of gastrin in the mucosa of this part compared to other areas of the
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