All patients were healed with no recurrent cases. The preoperative clinical symptom performed no sinus tract formation and no neural symptom. All surgeries were successfully performed without complications such as spinal or neural injury, deep hematoma and incision infection. Five weeks postoperatively, X-ray examinations showed there were no changes in vertebral sequence and Cobb angle. The duration of local chemotherapy before regression of symptoms, and hematologic and radiological abnormalities ranged from 2 to 9 months (average: 4 months) (Fig. 4,5). 42 patients had been followed up and the follow-up term was from 1.2 to 8.5 years (average 60 months).
The ODI and VAS scores performed significant difference between pre-operation …show more content…
In traditional method of systemic pure chemotherapy for bony tuberculosis, medicines cannot enter into the core of necrotic liquefied nidus so it takes long time to control pathogenetic condition with low rate tuberculosis13-16. Abscess, sequestrum and nerve complications constitute the common indication of nidus radical surgery. In 1950s, spinal tuberculosis surgery was proposed and the rate of death was largely reduced. However, there are some problems of indication surgery, which refers to big trauma, high relapse, and high expenses. In our study, local spinal tuberculosis therapy was replaced by minimally invasive tuberculosis puncture catheter drainage and local chemotherapy with minimal incision and extracted pus and tubercule bacillus locally. This method could augment drug concentration, kill tubercule bacillus quickly, and restrain malgenic elements of sinus tract formation with the help of local medical chemotherapy, which was the main reasons for our cases with no sinus tract formation in drainage …show more content…
Thus radical operation for tuberculosis should no longer be used to cause severe trauma to the patient. The drainage tube effectively removed the abscess and relieved spinal cord compression with little damage to the paravertebral muscle and minimal iatrogenic injury17. Moreover, this approach was time-effective. With regard to kyphosis, chemotherapy alone has been reported to result in an average increase in the Cobb angle of 15° and greater than 60° in 3-5% of cases. Open drainage is not recommended for tuberculous abscesses due to hard healing for sinus tract formation. In this study, close drainage was applied for the patients to avoid secondary infection or sinus tract. Abscess drainage has a low requirement for the patient's overall condition and does not require adequate preparation for chemotherapy before treatment. The local abscess drainage abscess can make the patient shrinks rapidly, and the local stimulation caused by the abscess and the symptoms of tuberculosis systemic poisoning can be relieved quickly. What’s more, the Cobb angle was from preoperative 5.90°±3.71° to postoperative 6.19°±3.85°, which had little increase after