Keloid Research Paper

Words: 976
Pages: 4

Abstract
Keloids are benign fibroproliferative scars that extend or originate outside the confines of the original lesion. They usually evolve at the anterior chest, shoulders, upper arms, cheeks, and ears and show the highest incidence in dark-skinned individuals aged between 20 and 30 years[1]. The efficacy of most pressure devices developed for the treatment of ear keloid is limited by the insufficient control of the applied pressure causing pain and increased bleeding with a subsequent increased risk of infection and cosmetic problem.[2]
Keywords: keloid, scars, pressure therapy.
Introduction
Keloids often develop on the ear, and are most frequently seen in younger females, the most common incidence being after ear piercing. They have also been reported to develop after otoplasty and other injuries of the ear. Ear keloids are
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Keloids form following dermal injury and exhibit exuberant, indefinite growth of collagen They tend to occur in darker skinned individuals with a familial tendency and not in the extremes of age. Keloid formation has been ascribed to altered growth factor regulation, aberrant collagen turnover, genetics, immune dysfunction, sebum reaction, and altered mechanics. Numerous hypothesis have been explained for keloid formation. The numerous treatments for keloids—surgical excision, steroid injection, radiation therapy, laser, silicone, and pressure therapy.[5] The first written description of keloids was attributed to the pyramid age in ancient Egypt. The term “cheloid” is derived from he Greek word “crab claw”, coined by Alibert in 1806.”Cosman et al., in the first systematic review of keloids, in 1961, documented the presentation, characteristics, and treatment of keloids in the. Mancini and Quaife, and later Peacock et al., differentiated between keloids and hypertrophic scars. Keloids and hypertrophic scars are separate entities- both clinically and