For decades, medical researchers around the globe have been seeking for treatments that would be able to clinically eradicate “the most common malignant pediatric brain tumor”1 in the world, or at the very least, notably extend its 5-year survival rate. Although many aspects of the molecular biology of medulloblastomas were formerly unclear, cancer research has made significant strides in the last decade and standard protocol methods are gradually being replaced by more innovative approaches that use targeted techniques. In order to move forward with optimal medical care and increase the survival rate of these children, patients and parental guardians must be more open to targeted therapeutic approaches as the biological understanding of medulloblastomas…show more content… For instance, radiation therapy is the most common form of postsurgical treatment for standard-risk (SR) patients because it has demonstrated to be incredibly successful in eradicating medulloblastoma tumors. However, this same treatment has shown to be particularly dangerous and commonly avoided in children younger than 3 years because their brains are developing significantly during these ages.3 Furthermore, patients who are given conventional treatments like craniospinal radiation or chemotherapy typically face long-standing medical issues, including “neurological deficits, cognitive decline, and secondary malignancies.”1 Even though these factors are well-known, families continue to deny clinical trials using targeted methods for their children due to the medical controversy that lies within these
