Multidrug Resistant Case Study

Words: 1233

Pages: 5

Open Document

Community acquired multi drug resistant (MDR) Pseudomonas aeruginosa and extended-spectrum beta-lactamase (ESBL) Escherichia Coli to ceftolozane-tazobactam in a patient with a liver abscess.

Mohamed Teleb M.D., Enrique Soto-Ruiz Pharm.D., Suresh Antony M.D
Section of Infectious Diseases, Department of Medicine
Texas Tech University School of Medicine, El Paso, Texas

Correspondence and Reprints:
Suresh Antony M.D
1205 N-Oregon
El Paso, Texas 79902
Tel: 9155334900
Fax 915 5334902
Email. Suresh.antony@att.net

Abstract
Multidrug resistant P.aeruginosa and extended-spectrum β-lactamase (ESBL) enterobactericae is becoming an increasing difficult clinical problem. De novo resistance to some of the new antimicrobials such as ceftolozane/tazobactam is unusual and is due to a variety of …show more content…
Post operatively she developed persistent abdominal pain with nausea and vomiting. She was evaluated in Mexico where she was noted to have a liver abscess and a percutaneous drainage catheter was placed. She then moved to the United States where she was admitted to the hospital for further …show more content…
aeruginosa and other gram-negative pathogens, including ESBL producing Enterobactericae [nccl]. Ceftolozane/tazobactam seemed to be an appropriate antimicrobial for our patient as it potentially provided coverage for both strains of pseudomonas as well as the ESBL-producing E. Coli. In addition, a regimen consisting of a single antimicrobial seemed more appropriate in the setting of C. difficle. After susceptibility testing and much to our surprise ceftolozane/tazobactam was not a viable option, as it did not inhibit any in vitro

Gram Negative Bacteria

Although multiple studies have been conducted to understand the emergence of multidrug resistant gram negative bacteria, the best nursing practice remains a challenge for the healthcare providers. In fact, no single treatment has been found to prevent or eradicate this phenomenon. One preferred practice would be early prevention and control of the spread of gram negative resistant bacteria in cancer wards. The use of chlorhexidine bath was shown to decrease gram positive bacteria colonization, but…

Words 807 - Pages 4

ANHB3321 Essay Submission

and treatment is effective in reducing mortality and morbidity of tuberculosis, saving up to 37 million lives between 2000 and 2013.2 As with many other infectious diseases, developing countries have the highest burden of disease with up to 95% of cases being found in these areas.2 Since the spread of tuberculosis requires a susceptible host and an environment that facilitates transmission, therefore any risk factor must increase exposure, susceptibility or both. This paper will cover these risk factors…

Words 2390 - Pages 10

Pseudomonas Aeruginosa Research Paper

Pseudomonas Aeruginosa is a gram negative rod-shaped bacterium that can cause disease in both plants and animals. It is resistant to antibiotics. Is considered an opportunistic bacteria causing cystic fibrosis. Pseudomonas Aeruginosa has a flagella and are motile. P. aeruginosa is not a fermenter of carbohydrates and has an optimal growth in aerobic atmosphere even through it will still grow slowly in an anaerobic environment if nitrate is present as the hydrogen acceptor. Pseudomonas Aeruginosa…

Words 1675 - Pages 7

Essay The Antibiotic Resistance Problem

antibiotics and other drugs he purchased at Methicillin-Resistant Staphylococcus aureus (MRSA) Gonorrhea his local pharmacy. He experienced intermittent periVancomycin-Insensitive Staphylococcus aureus (VISA) Head lice ods of coughing, fever, and fatigue for several weeks, finally consulting his physician who found small Vancomycin-Resistant Staphylococcus aureus (VRSA) Malaria bleeds under Mr. C’s skin, and decided to run blood Vancomycin-Resistant Enterococcus (VRE) Pneumonias tests. The diagnosis…

Words 5669 - Pages 23

Essay on Micro-Organisms and Antibiotic Resistance

kill or slow down the growth of bacteria that causes infectious diseases (Department of Health, 2014). Antibiotics are used to treat and prevent infectious bacterial diseases in humans and in domestic and food-producing animals. If bacteria become resistant the antibiotics become ineffective. Penicillin is the first antibioticdiscovered by Alexander Fleming in1928. Penicillin is used as an antibiotic drugfor many years and it helped to control the widespread occurrence of a disease. This drug is very…

Words 3308 - Pages 14

Epidemiology Essay on Tuberculosis

Laboratory tests to determine resistance for this strain can take several weeks which can delay treatment. Cure rate for MDR-TB is less than 50%. In 2006, a study done in Africa discovered a new strain called extensively drug-resistant TB (XDR-TB) in HIV infected individuals. The CDC and WHO have identified this newest strain in 17 countries including the US which accounts for 4% of the population infected with XDR-TB. (lung.org) Treatment…

Words 1739 - Pages 7