Zebrafish (Danio rerio) has recently emerged as a good in vivo vertebrate model for studying the process of myelination. Due to the rapid early development of its embryos, myelination can be observed around 60 hours post fertilization, as compared to the post-natal myelination in mammals (Buckley CE, 2010). Despite the vast genetic distance between …show more content…
This is possible as the zebrafish larvae are transparent, and it is possible to obtain mutant strains that sustain the transparency through to adulthood. It allows in vivo visualization of the CNS, which is valuable in carrying out functional imaging studies of neural activity and neural development (Panier, 2013; Misha B Ahrens, 2013). It is through such studies that the physical aspect of myelination has been observed and understood. In a recent study, the researchers were able to observe and test the assembly of myelin layers in the CNS, for the first time (Nicolas Snaidero,