Neutropenic fever is one of the hematological emergencies responsible for significant morbidity and mortality. Without early antibiotics, it has a mortality rate of 70%. Risk stratification tools are available to triage severity of illness and appropriately manage these patients. MASCC scoring system is a well-validated risk stratifying tool used to treat patients in the appropriate medical setting. Well-established clinical guidelines are available from IDSA to guide clinicians to manage Neutropenic Fever appropriately. Our study aim was to recognize deficiencies in management and assessing adherence to standard guidelines set by IDSA to manage patients with Neutropenic Fever.
Methodology:
This retrospective observational …show more content…
The study population was comprised of 52% male and 48% female patients with age range from 32 to 90 years. Hematological malignancies (36.5%), lung cancer (15%), breast cancer (10.5%) and colorectal malignancies (10.5%) were the top four oncological diagnoses. Subjective or objective record of fever was recorded in 54.6% (87/141) of the study population. MASCC score was calculated using QxMD online calculator for each patient. We saw
• After MASCC score calculation 82% (116/141) patients were identified as high risk with the score < 21 and 18% (25/141) were identified as low risk with score ≥21. Antipseudomonal coverage was appropriately given in 81% (114/141) of the patients. Sub-optimal coverage with non-pseudomonal agents was seen in 19% (27/141) of the patients while 5% of the patients did not have blood cultures drawn at the time of admission. MRSA coverage with vancomycin was given to 50% (71/141) of the patients without clear indications. A colony-stimulating agent was given to 72% (102/141) of the patients. Environmental precautions were ordered in 54% of the patients. Sixty-three percent of the patients were discharged home after full recovery while 23 percent patients were discharged to a secondary medical facility for further