What is the difference between a'smart' and a'smart'? What are the possible differential diagnoses at this time? Menopause, pregnancy, hypothyroidism, hyperprolactinemia, malignancy such as breast cancer, endometrial carcinoma, or ovarian cancer. 4. What is the difference between a.. What tests should you order and why? Pregnancy tests are done to rule out pregnancy. Serum TSH and Prolactin can be ordered based on the physical examination findings of symptoms of hyperprolactinemia or thyroid disease such as goiter, tachycardia, or galactorrhea. Patients who are 45 years and older presenting with irregular menstrual cycles and menopausal symptoms do not require additional diagnostic evaluation. High FSH and LH concentrations and low estradiol concentrations are normal in menopause or normal in premenopausal. Changes in menstrual bleeding patterns are a better predictor of menopausal stage compared to serum FSH concentrations. 5. What is the difference between a'smart' and a'smart'? How should this patient be managed? If a patient was diagnosed with perimenopause, her symptoms could be managed by administering either oral or transdermal cream of 17-beta estradiol based on patient preference and cyclic administration of oral micronized progesterone 200 mg/day for the first 12 days of each