Chronic wounds take a large and growing toll on the health and quality of life of people around the world and result in rising health care costs as well as losses in individual and societal productivity. In current practice, the edges of chronic wounds are visually examined to distinguish healthy tissue from tissue that requires treatment. However, visual inspection may only identify a “presumptive healing edge” — not the true healing edge — resulting in treatments that may be sub-optimal and that leave behind a margin of seemingly healthy tissue that may actually impede the wound healing process. To address this problem, Dr. Marjana Tomic-Canic (Weill Cornell Medical College) and her colleagues have proposed analyzing genetic markers in the