HEMATOPOIESIS
Lyn is required for normal stem cell factor–induced proliferation and chemotaxis
of primary hematopoietic cells
Bridget O’Laughlin-Bunner, Nina Radosevic, Marcia L. Taylor, Shivakrupa, Candy DeBerry, Dean D. Metcalfe, Meijuan Zhou,
Clifford Lowell, and Diana Linnekin
Stem cell factor (SCF) binds to c-Kit and
is an important mediator of survival,
growth, and function of hematopoietic
progenitor cells and mast cells. Lyn and
other Src family members are activated
by SCF…
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