Sickle-cell anemia is a specific form of anemia caused by a mutated hemoglobin allele that distorts the red blood cells into a crescent shape at low oxygen levels. Balanced polymorphism is where two different versions of a gene are maintained in a population because it helps the organisms survive better. Sickle- Cell anemia is an excellent example of balanced polymorphism because people with both types of b-globin sickle-cell alleles develop red blood cells that resist the cause of malaria. People with two copies of the B-globin sickle cell allele will end up developing sickle-cell disease and will have a shorter life span. In this case mutation helps the organism survive, hence, a great example of balanced