Type 1 Diabetes Case Study

Type 1 diabetes (T1D) is identified by the autoimmune destruction of pancreatic β cells. The swift climb in T1D percentage during the past 50 years advocates environmental circumstance contribute to the disease. Diabetes in the United States afflicts 8.3 percent of the population with an annual cost of 200 billion dollars a year (Greiner, 2011). Scientists believe the gut microbiome goes through a period of extraordinary reshaping from birth until 3 years of age when it shifts composition (Alexandra, 2017) which can influence diabetes. The newborn’s microbiome depends on consignment and is determined during infancy by breastfeeding and the introduction of solid foods. The effect of numerous environmental, dietary, and lifestyle factors has …show more content…
But sometimes the genetics is so strong that it will override and drive back the microbiota. Identifying, the individuals who are at risk before disease onset is key for establishing a treatment plan that can impact pancreatic autoimmunity health.
Rodent models, particularly the Non-obese diabetic mouse (NOD), have provided a wealth of data regarding the complex genetic etiology and breakdown of immunological tolerance in T1D (Alexandra, 2017). The rodent is used as a model for type 1 diabetes and they are indicated by hyperglycemia and insulitis. Studies has shown that with decrease in pancreatic insulin content 90 percent of females and 52 percent of males became diabetic by 30 weeks …show more content…
Frank Greenway and his research team have found that short-chain fatty acids created by gut bacteria that can affect insulin production. When, fatty acids numbers are in decline, this affect the output of insulin. Researchers in a clinical study developed a mixture containing polyphenol from blueberries and dietary fiber from oats, which encourages the microbes to grow. The test subjects were given this drink twice a day for four weeks. The results showed those who were taking the mixture had higher levels of insulin after a meal than those who didn’t take the drug (Medical revolution, 2015).
My current level of knowledge about gut microbiome was zero before this lesson. The assigned me opened my eyes about a deadly condition that has killed a lot of people in my family. The research that Dr. Greenway needs to be advertised more throughout the black committees. Many people are afraid of using a needle for insulin ejections, and this fear leaves them very low chances in taking the shot that will keep them alive. I feel that many of them would prefer to have a drink that would increase their levels or using a

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