The rise of government forced Native American’s to be pushed West or killed off in order for the European colonists to begin settling on the land and setting up more trade routes. In Changes in the Land, Cronon writes “by 1800, Indians could no longer living the same seasons of want and plenty that their ancestors had, for the simple reason that crucial aspects of those seasons had changed beyond recognition.” (Cronon 169) Moreover one of the most drastic results of European settlement was the spread of disease. Not only did they spread typical Europeans disease but also epidemic from the Old World such as malaria, yellow fever, and smallpox, among several others. The Native Americans were tremendously healthy people but because they had never been subject to these types of organisms a large percent of them