The concept of sin in Macbeth is shown as an interaction between the witches, forces of nature, and the human life’s that it affects. Evil causes a loss of closeness or fellowship with God. The results of this loss show up in many different forms throughout the play. For example, Lady Macbeth shows an alienation from herself at the end of the play, and ultimately commits suicide. Macbeth felt a loss of dominion over his own life as his troops turned against him. Shakespeare