Biochemistry-Metabolism Essay

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Western Governors University

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Hereditary Fructose Intolerance
Metabolism is the process of cellular respiration. It involves three steps, 1) glycolysis, 2) the citric acid or Krebs cycle and 3) electron transport system. The glycolytic pathway or glycolysis is a metabolic process that leads to the formation of the energy source adenosine triphosphate (ATP) in the body. ATP is essential to the cell and the cellular processes used by the cell. The first step, glycolysis is the process by which each molecule of glucose is converted to two pyruvate molecules, creating two ATPs and two nicotinamide adenine dinucleotide (NADH).
NADH is also converted to four ATPs during the electron transport chain.
An enzyme is a protein or
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These ions are then transferred back across the membrane through an enzyme ATP synthase. The ions and energy are then released in the form of ATP (Hudon-Miller, 2012).
Coenzyme Q10 plays an important role in the conversion of NADH and FADH2 to ATP.
Coenzyme Q10 is a fat-soluble enzyme that is transportable through the cell membrane. It is an electron carrier in the electron transport chain. As it gains electrons it becomes oxidized and as it loses them it is reduced. The electrons begin at NADH (Complex 1) and move to Coenzyme
Q10 which then transports the electron to the second complex. These electrons pass through the inner membrane of the cell, from complexes 1-4, hydrogen ions are released into the intermembrane space. The end product of this process is the creation ATP which account for over 90% of the body’s energy (Hudon-Miller 2012, Wikipedia 2013)

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References
Energy, ATP, and Enzymes. Retrieved on February 28, 2013 from http://www.uic.edu/classes/bios/bios100/lectures/enzymes.htm Genetic People. (2011). Fructose 1-Phosphate Aldolase Deficiency (Fructose Intolerance).
Retrieved on February 26, 2013 from http://geneticpeople.com/?p=882.
Hudon-Miller, Sarah. 2012. Cori Cycle. Video retrieved from http://www.youtube.com/watch?v=gWXDNBiLva4&feature=youtu.be. Hudon-Miller, Sarah. 2012. Enzymes and Fructose Breakdown. Video retrieved from