Biophysics aspect of the module was evidently new to me, aswell as the calculation and detection of blood pressure, and mean arterial pressure. Hypertension, arthrosclerosis are the main co morbid factors of cardiovascular disease. It would seem there are various tests to check for hypertension, like lipid profile, to check cholesterol levels which could state the thickness arteries a clinical sign of hypertension; urea and creatinine test, to evaluate the health of the kidneys, as hypertension is strongly correlated with kidney disease, furthermore renin and aldosterone blood tests. These tests I could encounter as a biomedical scientist in a pathology laboratory, and I must ensure I understand what the results interpret and …show more content…
Inflammation is a key sign in coronary heart disease and arthrosclerosis, so studies of inflammatory biomarkers have been carried out in order to produce better treatment strategies. The question is what is special about CRP as an inflammatory biomarker than the rest; well the article answers this by its measurement being cheap and its high specificity in prognosis of CHD, and its surplus amounts of high sensitivity assays furthermore its discusses the biological role it portrays in artherogenesis through various mechanisms like complement pathway activation, lipid uptake and its inhibition of nitric oxide. Arthrosclerosis is caused by inflammation in the endothelium tissue in the coronary arteries; this action demonstrates increase levels of inflammatory biomarkers. Recent studies indicate high levels of CRP are correlated with CHD, regardless of gender, age, and diversity. I learnt about the structure-function of CRP, such as, it’s a protein produced by liver cells, in response to interleukin 6 and is part of the pentraxin family of calcium dependent ligand-binding plasma proteins and also its historical foundation which was evidently new to me. Secondly, the article stresses, that High sensitive CRP is no different to the standard version of CRP, and that there discrepancies, in areas of research. It’s in my belief that this article is very important, as it clearly