for only 20-25% of disease occurrence. However,
among these factors, several are related to sex steroid
hormones: sex of the affected individuals [women), early
age of menarche and late age of menopause, parity, late
age at first pregnancy, and obesity in postmenopausal
women.
Methods. Theoretical models and laboratory data
support hormonal mechanisms of carcinogenesis, particularly as they relate to proliferation of breast ductal epithelium and terminal end bud growth and differentiation
in…
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