Elevated Blood Pressure Case Study

Words: 620
Pages: 3
Open Document
SPRINT Elevated blood pressure (BP) is an important public health concern. It is highly prevalent and a risk factor for several adverse health outcomes, especially coronary heart disease, stroke, heart failure, chronic kidney disease, and decline in cognitive function. The Systolic Blood Pressure Intervention Trial (SPRINT) was designed to test whether a treatment program aimed at reducing systolic blood pressure (SBP) to a lower goal (120mmHg) than currently recommended (140mmHg) could reduce cardiovascular disease (CVD) risk. The SPRINT study enrolled more than 9 000 people from USA. It included patients aged over 50, with SBP from 130 to 180 mmHg and at least one associated item: additional CVD risk, clinical or subclinical CVD …show more content…
The Intensive arm had a goal of SBP <120 mm Hg. One or more medications from the following classes of agents were provided by the study: Angiotension converting enzyme (ACE)-inhibitors Angiotension receptor blockers (ARBs) Direct vasodilators Thiazide-type diuretics Loop diuretics Potassium-sparing diuretics Beta-blockers Sustained-release calcium channel blockers (CCBs) Alpha1-receptor blockers 2. The Standard arm had a goal of SBP <140 mm Hg. Therapy was intensified if SBP ≥160 mm Hg at 1 visit; ≥140 mm Hg at 2 consecutive visits; Down-titration was done if SBP <130 mm Hg at 1 visit; <135 mm Hg at 2 consecutive …show more content…
2.19% per year hazard ratio 0.75; 95% CI: 0.64 to 0.890) resulting from the reduction of Heart failure and Cardiovascular Death while (surprisingly) no reduction of Stroke was noted. All-cause mortality was also significantly lower in the intensive - treatment group (hazard ratio, 0.73; 95% CI, 0.60 to 0.90; P=0.003). The numbers needed to treat to prevent a primary outcome event, death from any cause, and death from cardiovascular causes during the median 3.26 years of the trial were 61, 90, and 172, respectively. These results were consistent across the pre-specified subgroups. There were no significant interactions between treatment and subgroups with respect to the primary outcome or death from any cause. A total of 220 participants in the intensive-treatment group (4.7%) and 118 in the standard- treatment group (2.5%) had serious adverse events (hypotension, syncope and acute kidney injury or failure) that were classified as related to the intervention (HR 1.88;
Show More

Related Documents: Elevated Blood Pressure Case Study

Respiratory Failure Case Study

Respiratory Failure Sepsis is defined as systemic inflammatory response syndrome in response to infection, and, when associated with acute organ dysfunction, it is considered severe sepsis (Durthaler, Ernest, & Johnston, 2009, p.45). As describe on the case study, septic patients can show a multi system infection process in response to the invading microorganism like bacteria, fungi, parasites, and viruses. What is the process involved in sepsis? The process involved in sepsis consists of the invasion of…

Words 1262 - Pages 6

Metabolic Syndrome

Patient Diagnosis Case Study: Metabolic Syndrome. Catherine Leiva Martinez University of Phoenix Master of Science in Nursing/Psychiatric Mental Health Nurse Practitioner Advanced Pathophysiology NRP/511 Vincent Smith May 21st, 2024. Introduction Metabolic syndrome is a complex and interrelated cluster of metabolic abnormalities that significantly increases the risk of cardiovascular disease and type 2 diabetes. This case study presents the assessment and diagnosis of a patient…

Words 784 - Pages 4

Medical Underwriting Research Paper

Doctors help in avoiding moral hazard. Last but the least all reports should be received with client identification slip and ID proof duly signed by the panel doctor with seal and signature. MER MER contains measurement of height, weight, blood pressure, abdomen girth, chest expansion and pulse. Assessing the details will help us in understand the health of the proposer in a broader…

Words 1068 - Pages 5

Essay on preeclampsia 2

and is associated with substantial morbidity and mortality for mother and affects 5-8% of the pregnant population. Preeclampsia is characterized by high blood pressure and signs of damage to another organ system, often the kidneys. Preeclampsia can be mild to severe, and usually begins after 20 weeks of pregnancy in a woman whose blood pressure had been normal. If not treated this can further progress into eeclampsia, HELLP syndrome, and then to DIC. Preeclampsia is defined as the presence of hypertension…

Words 651 - Pages 3

Diabetes Intervention Analysis Paper

Abstract This paper is an intervention analysis based on the case study of a 11-year-old girl diagnosed with DKA whose outcome unfortunately was fatal due to the severity and complexity of her disease and its process. This paper will describe the physiology and pathophysiology of the diabetes-related complication Diabetic Ketoacidosis(DKA), the organs or systems that is involved, and how it impacting diabetes. In addition, the significance of this diabetes related condition within a child…

Words 475 - Pages 2

Arf Case Study Essay

ARF Case Study Acute Renal Failure Case Study Directions: Please carefully read the following case study and answer the following questions in typed format. The resources that you will need to complete this case study include your textbook and drug book. Please include in text citations. This independent assignment is worth 25 points. Ann Hayes, age 68, initially was admitted to the hospital for elective surgical repair of an abdominal aortic aneurysm. Her surgery was documented…

Words 2501 - Pages 11

Essay on Pathophysiology HTN

which the systolic blood pressure is greater than 140 mmHg or the diastolic blood pressure is greater than 90 mmHg. Related Diagnostic Tests: Basic lab studies; history and physical; UA; metabolic panel; serum lipids; ECG; 24-creatine clearance, ECHO; liver function; TSH; BP monitoring; sleep studies, and ultrasounds of vessels Etiology: HTN is either primary or secondary. Primary (essential or idiopathic) is elevated BP without an identifiable cause, occurring in 90% of all cases. Factors may include…

Words 447 - Pages 2

Essay on Chronic Obstructive Pulmonary Disease (Copd; Emphysema) Patho

emphysema is related to a high percentage of CD4+ and CD8+ T lymphocytes that expressed chemokine receptors CCR5 and CXCR3 which are both indicators of T helper 1 cells, but not CCR3. Lung lymphocytes in patients with COPD and emphysema such as in the case of D.Z., secretes more interferon gamma, often associated with T helper 1 cells and interferon-inducible protein 10 and monokine induced by interferon, both of which bind to CXCR3 and are involved in drawing T helper 1 cells. In response to interferon-inducible…

Words 6928 - Pages 28

Adequate Coronary Syndrome (ACS)

or may not radiate. Patients can present with dyspnea, diaphoresis, pre-syncope, palpitations, tachycardia, tachypnea, changes in blood pressure, decreased saturation and rhythm abnormalities. [1][2][6] These symptoms occur at rest or with exertion and limit activity. Diagnostic findings include ST depression or T-wave inversion on ECG. Cardiac biomarkers are NOT elevated. NSTEMI is caused by a similar event as unstable angina and presents in a similar way, the only difference being that the duration…

Words 2098 - Pages 9

Raised Intracranial Pressure Lab Report

Raised intracranial pressure (ICP) is a common life-threatening condition that can occur in multiple neurological or non-neurological settings.Traumatic brain injury (TBI) is one of the main causes of increased intracranial pressure .Raised intracranial pressure has multiple catastrophic results as it decreases the cerebral blood flow and causes global iscahemia to the brain leading finally to brain death.(1) There is a multiple methods to monitor the intracranial pressure either invasive…

Words 1068 - Pages 5