FicationSite of Synthesis Site of Release Target Tissue Hormone Action Regulation Pathology
Oxytocin
(Positive) NeuroPeptide HypothaPos.
Pit. (Epithilial cells)
Smooth muscle and vans deferens Responsible for contraction of milk ducts and smooth muscle Receptors that sense activity in breast NONE
* Observations in decrease in bonding of baby and parent
Anti-Diretic Hormone (Vasopressin) Peptide HypothalPos. Pit Kidney 1. BV, BP via decrease in osmolality in urine
2. Constriction of blood vessels 1. Low BP
2. osmolality in urine
BP Inapproiate secretion of ADH; Insufficient/ Resistance (opposite)
Growth Hormone
Growth Hormone (con.) Peptide Anterior pit. Anterior pit. Fat, liver, muscles
(Nonendo-
crine system) Tissue growth and metabolic action (anti-insulin) Inhibits GHRH release, stimulates GHIH Circadian rhythm, stress, and cortisol -Gigantism *adolescence
Very tall (Excess GH before epesilial cell close)
-Acromegaly lengenthing of jaw *adulthood ( Excess in GH after epesialial plate closes)
-Dwarfism *adolescence (Not enough GH)
Glucocorticoids (Cortisol)
(negative) Steroid zona fasciculata of the adrenal Cortex zona fasciculata of the adrenal Cortex Liver, muscle, adipose tissue Suppresses immune system, stimulates making of glucose (gluconeogenesis);
Aids in fat, protein, and carb metabolism CRH, ACTH, Cortisol;
CRH, ACTH, Cortisol; Cushing Syndrome (Buffalo’s Hump) thin limbs and fat around stomach. Caused by protein catabolism;
Hyperglycemia (Low Cortisol, counteracts insulin *antagonistic?
Thyroid Hormone Amine Thyroid gland Thyroid gland Most cells in the body Excessive