Metabolic Response To Injury Case Study Essay

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Pages: 5

Case Study 4
John recently suffered a gunshot wound to the abdomen and has undergone surgery. He is 37 years old, 6’ 0”, and weighs 200 lbs. John is currently on a medical ventilator to help him breathe.
1. Describe the metabolic response to injury (ebb phase and flow phase). If you do not understand certain terms (such as hemodynamic instability), please attempt to do further research.

A person’s body undergoing a metabolic response to injury is in severe stress. The body reacts to this injury immediately through a series of ebb and flow states showing the persons response to the trauma they are undergoing. The first phase, called the ebb phase happens in response to the injury, in this case a gunshot wound to the abdomen, and immediately
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Systemic vasodilation and the associated decrease in peripheral vascular resistance results in decreased pulmonary capillary wedge pressure and decreased blood pressure, presenting usually with a collapsing pulse, but sometimes a bounding pulse https://en.wikipedia.org/wiki/Hyperdynamic_circulation
Proteolysis **: the breakdown of proteins or peptides into amino acids by the action of enzymes. www.dictionary.com/browse/proteolysis

gluconeogenesis ***: is the process that leads to the generation of glucose from a variety of sources such as pyruvate, lactate, glycerol, and certain amino acids. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/gluconeogenesis hyperglycemia ****: A high blood sugar. An elevated level specifically of the sugar glucose in the blood. https://www.medicinenet.com/script/main/art.asp?articlekey=3836
Tumor Necrosis Factor alpha (TNF alpha)*****, is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis. This protein is also important for inflammation and cancer.
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and Gilbert, J. ed., (2015). Williams' Essentials of Nutrition and Diet Therapy. In: Williams' Essentials of Nutrition and Diet Therapy. pp. Chapter 9 pgs199-221.

"Definition Of Hyperglycemia." MedicineNet. N.p., 2018. Web. 5 Mar. 2018.
"Gluconeogenesis - An Overview | Sciencedirect Topics." Sciencedirect.com. N.p., 2018. Web. 5 Mar. 2018.

"Hyperdynamic Circulation." En.wikipedia.org. N.p., 2018. Web. 5 Mar. 2018.

"Interleukin | Protein." Encyclopedia Britannica. N.p., 2018. Web. 5 Mar. 2018.

JH, Idriss. "TNF Alpha And The TNF Receptor Superfamily: Structure-Function Relationship(S). - Pubmed - NCBI." Ncbi.nlm.nih.gov. N.p., 2018. Web. 5 Mar. 2018.
"Proteolysis | Define Proteolysis At Dictionary.Com." Web. 5 Mar. 2018.

"Reference Cards." Med-ed.virginia.edu. N.p., 2018. Web. 4 Mar.