One of the key points of this story is resistant nature of the protagonist, who refuses to obey the "mill" (system) and goes ahead.
Examples: conflicts with the nurse, violation of order of the system, keeping a positive attitude.
The line between madness and prudence is vital issue that underlies the plot, and give food for thought about what really is right and what is absurd.
Examples: lobotomy, fear to show emotions, making people inhibited and