Opiate is the term used for any drug derived from the opium poppy, they all share the same generalised structure shown in figure 1. The most commonly known opiates are opium, morphine, codeine and morphine. All of these are potent narcotic analgesics which means they cause a drowsy sensation and relieve pain, and are used for recreational and medicinal purposes.
The Opium poppy can be traced back to 3400 B.C when they were first cultivated in Mesopotamia, and eventually became recognized for its power as a narcotic by greek philosopher Hippocrates. Over time the poppy was spread throughout the world, and even became the cause of war between China and England.
In 1806, Morphine was extracted from opium by german chemist Friedrich Wilhelm Adam Sertüner, a huge step for modern medicine in understanding surrounding isolation leading to the discovery of many other pure drugs. Morphine was named after the Greek god Morpheus, the God of Dreams, and became very popular during the American Civil War causing many soldier to become addicted to it. Because of it’s high addiction liability, there has been many attempts to chemically alter the structure of morphine in effort to develop a drug with the same benefits, but a significantly lower dependence risk; leading to the creation of Heroin and many other derivatives from a process known as acetylation. Acetylation is the process where an acetyl functional group is introduced into a chemical compound, while the opposite reaction , deacetylation is the removal of the acetyl group. …show more content…
Heroin can be administered orally, by injection, inhaling, as a suppository, or insufflation and is linked to a rise in HIV/AIDS