Premature Menopause Research Paper

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Affected Glands & Normal Functions: Premature Menopause affects multiple endocrine glands, the hypothalamus, anterior pituitary gland, and ovaries can all be affected by premature menopause.
• The normal function of hypothalamus in the body is to produce releasing and inhibiting hormones, which stop and start the production of other hormones throughout the body. It also regulates the secretion of anterior pituitary gland hormones.
• The normal major function of the anterior pituitary gland is to synthesize and secrete six major hormones in the body: Human Growth Hormone (hGH), Prolactin (PRL), Thyroid-Stimulating Hormone (TSH), Adrenocorticotropic Hormone (ACTH), Follicle-Stimulating Hormone (FSH), and Luteinizing Hormone (LH).
• The normal …show more content…
Premature menopause shows signs of hereditary, and has been statistically concluded to have a higher chance of developing in a family with a previous history of premature menopause.
Symptoms:
Symptoms of Premature Menopause vary amongst different patients, however the most common symptoms include: Irregular or skipped periods, abnormal amounts of menstrual blood, Hot Flashes (sudden warm feelings). These symptoms are caused by insufficient estrogen amounts produced from the ovaries. Some women might also experience: vaginal dryness, bladder irritability, mood swings, dry skin, sleepiness, and decreased sex …show more content…
Follicle Depletion could be caused by:
• Chromosomal defects because certain genetic disorders are associated with premature ovarian failure. These include Turner's syndrome, a condition in which a woman has only one X chromosome instead of the usual two, and fragile X syndrome, a major cause of intellectual disability (intellectual development disorder).
• Toxins, because chemotherapy and radiation therapy are the most common causes of toxin-induced ovarian failure. These therapies may damage the genetic material in cells. Other toxins such as cigarette smoke, chemicals, pesticides and viruses may hasten ovarian failure.

Follicle Dysfunction may be the result of:
• An autoimmune response to ovarian tissue, which is the body’s immune system attacking the ovary tissues. The immune system may produce antibodies against your own ovarian tissue, harming the egg-containing follicles and damaging the egg. What triggers the immune response is unclear, but exposure to a virus is one
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