Pushing Syndrome Research Paper

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Endocrine disorders

1- Cushing syndrome - a genit

**Definition** Hormonal disorder Cushing syndrome is brought on by extended exposure to elevated cortisol levels. This can happen as a result of the body overproducing cortisol or from using corticosteroid medicines.

**Causes** - Exogenous Cushing syndrome: Long-term use of corticosteroid medications like prednisone - Endogenous Cushing syndrome: - Pituitary adenoma (Cushing's disease) - Excess ACTH production from pituitary tumor - Adrenal adenoma or carcinoma - Excess cortisol production from adrenal gland - Ectopic ACTH syndrome - Excess ACTH production from non-pituitary tumor - Excess AC

**Clinical Pictures** - Weight gain, especially in the abdomen, face, and upper back - High blood pressure - Diabetes or impaired glucose tolerance - Facial rounding ("moon face") - Thin, fragile skin that bruises …show more content…
The most prevalent cause of primary adrenal insufficiency is autoimmune destruction of the adrenal glands. Secondary adrenal insufficiency is brought on by a malfunction in the pituitary gland's ability to produce ACTH, which is necessary for the adrenal glands to be regulated. Congenital adrenal hyperplasia: A hereditary condition that impairs the production of adrenal hormones. Damage to the adrenal glands brought on by infections, trauma, cancer, or specific drugs.

**Medical Images** - Weakness and fatigue - Reduced weight and appetite - Diarrhea, vomiting, and nausea - Skin hyperpigmentation, encompassing wrinkles, scars, and mucosal membranes - Hypotension, or low blood pressure, particularly when standing - A need for salt - Pain in the muscles or joints - Anger and sadness.

**Medical Examinations** - Blood tests to assess electrolytes, cortisol, and ACTH levels - Adrenal gland CT scan - Cosyntropin stimulation test to evaluate adrenal
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