Skeletal Muscle Research Paper

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1. Introduction
1.1 Muscle
Muscle is a type of smooth tissue found along the animal kingdom. It is one of the four major types of tissue in animals. Muscle is been divided in three subgroups: skeletal muscle, cardiac muscle and smooth muscle. Muscle cells, that forms the muscle, contain filaments of actin and myosin that slide one over the other and has us a result the contraction of the cell thus change the shape and the length of the cell itself. The main function of muscle is to create motion and force. Muscles are mostly responsible for maintaining and changing position and motion of the body, as well as movement of internal organs, such as the movement of food through the digestive system through process called peristalsis as well as …show more content…
Several single nucleated cells fused together to form the multinucleated muscle fibres. Muscle fibres are consisting of myofibrils which are rod-like elements(Brooks, 2003). Myofibrils are consisting of repeated essential units called sarcomeres. The two main proteins that make up the sarcomeres are the actin which is the thin filament and the myosin which is the thick filament. Those two proteins are responsible for the mechanism necessary for muscle contraction. The muscle fibres can be divided into two categories depending on histochemical analysis, Type I which is the slow muscle fibres and type II which is the fast muscle fibres (Schantz, 1986). Skeletal muscle tissue, like all other tissues, is formed during embryo development through a process known as myogenesis, which is also induced upon stimulation in adults during the regeneration of skeletal muscle.

1.2 Myogenesis
Myogenesis is the process that forms the muscular tissue. Myogenesis is a complex tightly regulated procedure During myogenesis, the myoblasts are pulled out from the cell cycle by the stimulation of the expression of the myogenic differentiation-specific genes and fused together to form a multi-nuclei fibres called myotubes (Sabourin and Rudnicki, 2000). Myogenesis occurs during different stages of human development. Specifically myogenesis takes place during the embryogenesis in order to form the muscle tissue and in adults for the replacement of damaged or lost muscle.

1.2.1. Myogenesis during
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