Systemic Lupus Erythematous (SLE)

INTRODUCTION Systemic Lupus Erythematous (SLE) could be one of chronic disease. SLE could be one of the fatal disease. In Latin lupus means wolf. They belief that this disease might me from the bites of this animal. It was discovered by physician Rogerius on thirteenth century. At 1872, Moriz Kaposi, a student and son-in-law of the Austrian dermatologist Ferdinand von Hebra divided lupus into two catogories that are systemic lupus erythematous and doscoid lupus. At 1948, a research had be made from a cell of patient's bone marrow. SLE be the one that recorded the highest cases compare to others.

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Systemic Lupus Erythematous (SLE) is a chronic inflammatory autoimmune disorder that appears in several …show more content…
However, there is also a delayed diagnosis that happened among women 37-50 years. For ethnicity, SLE more prevalent among people of Afro-Caribbean origin, followed by Asians and then Caucasians. From the studies among population in Australia and New Zealand shows that higher rates of occurrence among aboriginals when compared with Caucasians. In contrast, the studies that carried out in China, the Philippines and Japan they found that Caucasians shows the higher rates. Surprisingly, the rates of occurrences appear to be low in West African countries. However, the rate of occurrence does not seem to purely affect by ethnicity but also the clinical presentation. For example, discoid skin lesions, cellular casts in the urine and serositis are commonly effect black …show more content…
It might takes months or even years before they can diagnose this complex disease accurately. The patients actually can help the doctors in diagnosing this disease. It can be done by giving a complete and accurate medical history. The result from physical examination and laboratory test helps the doctor to diagnose lupus. They can even consider other diseases that may mimic lupus.
Antinuclear antibodies(ANA) is one of the way to diagnose lupus. Antinuclear antibodies are autoantibodies that bind to contents of the cell nucleus. In normal individuals, the foreign proteins(antigens) get the antibodies from the immune system. But it will be differ for human proteins (autoantigens). In some individuals, antibodies to human antigens are produced. Autoantibody screening is useful in the diagnosis of autoimmune disorders and monitoring levels helps to predict the progression of disease.
We also can diagnose SLE using laboratory test. Urinalysis is an example of laboratory test. An affected kidney show an increase in protein level or red blood cells in the sample of the urine. Another laboratory test is complete blood count (CBC) . This test measures the number of red blood cells, white blood cells and platelets as well as the amount of haemoglobin, a protein in red blood cells. Results may indicate you have anaemia, which commonly occurs in lupus. One that have been diagnosed by SLE also have a low white blood cell and platelet

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