Breast Cancer Research Paper

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“One in eight women will be diagnosed with breast cancer in her lifetime”(National Breast Cancer Foundation). Breast Cancer, also known as Mammary Cancer and Breast Carcinoma, is one of the most popular genetic disorders in the world. In the early centuries, Breast Cancer was recorded constantly, due to the noticeable symptoms and tumors. Back in ancient times, Hippocrates explained Breast Cancer as “the wandering womb.” Medical researchers made a lot of hypotheses and theories about the causes of Breast Cancer throughout history. Until the 19th century, Breast Cancer was still considered a rare disease. In 1923, Janet Claypon, one of the founders of epidemiology, did the first large scale study on women with breast cancer. Her research discovered …show more content…
BRCA1 and BRCA2 are two examples of most inherited cases of Breast Cancer. The inheritance pattern for both genes is autosomal dominant trait. BRCA1 is located on chromosome 13, and BRCA2 is located on chromosome 17. Everyone has BRCA1 and BRCA2 genes in his or her body, and they keep our breast cells growing normally and fix damaged DNA; however, once one of the genes becomes mutated, it will no longer function normally and cancer will most likely to develop in your body. BRCA1 and BRCA2 are both tumor suppressor genes; “BRCA genes are considered high-penetrance”(Cancer.org), which means that they are more likely to lead to cancer. A damaged chromosome is found inside of a woman, who inherited either mutated BRCA1 or BRCA2 genes. Also, a man can develop breast cancer, when he inherits the tumor suppressor genes. Furthermore, researchers recently found another mutation chromosome called SNPs, that may also lead to the same effect as the BRCA1 …show more content…
When the Breast Cancer emerges, externally, the size the shape of the breast would change. The internally changes of Breast cancer vary by the types. There are three common types of Breast Cancer: Ductal Carcinoma in situ, Invasive Ductal Carcinoma and Invasive lobular Carcinoma. Ductal Carcinoma starts inside of the milk ducts, and it is the only part that could be affected. Since Ductal Carcinoma is non-invasive, it would not spread the cancerous cells to other tissue. Ductal Carcinoma would not be life-threatening; however, it could develop into a invasive cancer. Invasive Ductal Carcinoma also begins inside of the milk duct, but over time, the cancerous cell might spread to the lymph nodes and other tissues. Invasive Lobular Carcinoma starts in the lobules, and it can spread to other areas in the
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