It is essential to have communication with patient based on their age and learning style. Dental personnel must keep in mind that patients with cystic fibrosis may require adaption to the dental office atmosphere. The patient might experience stress, fear or anxiety based upon previous encounters with dental treatment, so it is important to make a good impression on the patient and make them feel comfortable. Always be prepared since patients with CF might need longer/shorter appointments. Certain times may affect the patients based on the severity of their condition, so it is recommended to ask the patient what time works best for their schedule and lifestyle. A dental indication of cystic fibrosis is that the enamel is commonly disfigured in patients with this condition. Regular visits to the dentist may can prevent this disfiguration. Therefore, it is essential CF patients have early access to good dental care. The prevalence of calculus in children varies widely depending on patient demographics, social class, and general health. Patients with CF have different amounts of calcium and phosphate in their saliva then the average person which can affect calculus formation. Antibiotic therapy can aid in helping prevent periodontal disease in CF