At this stage, memory loss is more noticeable and patients need some assistance to complete their daily activity. Also, loss of mobility, difficulty in communicating and weight loss are the symptoms at this stage. Incontinence, loss of bladder control, compulsions or anxiety are also changes that may occur. Treatment is required at this stage and it is often medication. For example, Donepezil and Memantine are used to slow the symptoms, Galantamine is used to prevent the symptoms. The average duration of this stage is between one and half to two and half