Multiple Sclerosis Research Paper

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More than 2.3 million people are diagnosed with Multiple Sclerosis worldwide. There are currently 250,000 to 350,000 people in the United States diagnosed with multiple sclerosis. And about 200 new cases are diagnosed every week (Multiple Sclerosis FAQs). Neurologists prescribe these patients with corticosteroids (steroids), either oral or through IV. Although scientists have found no cure to multiple sclerosis, Corticosteroids have been used to successfully treat relapses and potentially stop progressive-relapsing and relapsing-remitting multiple sclerosis.
To start off with, multiple sclerosis is a disease of the central nervous system (CNS). It damages the protective coating around the nerve fibers that sends messages to all parts of your …show more content…
Symptoms multiple sclerosis are different for every person; usual symptoms multiple sclerosis of relapses include optic neuritis, limb weakness, numbness, imbalance, light-headedness, and loss of facial strength. In more serious multiple sclerosis, such as in progressive-relapsing multiple sclerosis, symptoms multiple sclerosis include fatigue, and depression. Relapses usually range from days to weeks and self-fixed around weeks to months. Neurologists use Corticosteroids for selected relapses that have reoccurring symptoms multiple sclerosis and increasingly get worse through-out the relapse. Around fifty percent of neurologists use them for all relapses (Mechanistic Insights…). This states that even patient that have the same type of multiple sclerosis as you, you may have different symptoms multiple sclerosis and be given different treatments for your relapses, dependent on how sever they may …show more content…
The symptoms multiple sclerosis they can treat with Corticosteroids usually consist of tingling in the absence of sensory loss. One major study done by N. M. Milligan, a researcher at University Hospital of Wales, stated that, “50 patients received methylprednisolone(MP) 500mg intravenously(IV) for five days or inactive placebo….carried out at 1 to 4 weeks….73 percent of MP-treated patients improved compared with 29 percent of MP-treated of those on placebo”. The group he tested on contained both relapsing-remitting multiple sclerosis and Chronic progressive multiple sclerosis, both these patients benefited from MP. This study made neurologists, around the world, to start prescribing IV MP for relapses. One other slightly major study done by Finn Sellebjerg, a professor of neurology at the University of Copenhagen and chief physician at Danish Multiple Sclerosis Center, gave 51 patients enduring a relapse less than four weeks to receive oral placebo or oral prednisolone (Corticosteroids) 500mg per day for five days. Results of Sellebjerg states “…1, 3, and 8 weeks, 4 percent, 24 percent, and 32 percent in the placebo group and 31 percent, 54 percent, and 65 percent in the prednisolone group improved one point on the Kurtzke Scale score” these patients also stated that their symptoms multiple sclerosis improved much more with the steroids at 3 and 8 weeks (Steroids). As you can
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