The skin component of SLE include facial erythema across the cheeks and nose. Severity of the disease can vary from mild to potentially fatal. SLE can occur in both male and female of all ages but it is eight times more common in woman than man. Mainly young women are affected. The 5-year mortality has been variously estimated to be between 15 and 50 per cent, dependent on the organ system affected and the pace of the disease. In addition, ‘’SLE may be due to alteration of nuclear constituents by infection or drugs and is associated with antinuclear factors in 80-90%’’ (R. Marks,