Overview: The Fundamental Units of Life
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All organisms are made of cells
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The cell is the simplest collection of matter
that can live
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Cell structure is correlated to cellular function
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All cells are related by their descent from earlier cells
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LMs can magnify effectively to about 1,000 times the size of
the actual specimen
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Various techniques enhance contrast and enable cell
components to be stained or labeled
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Most subcellular structures, including organelles (membraneenclosed
compartments), are too small to be resolved by an
LM
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Two basic types of electron microscopes (EMs) are used to
study subcellular structures
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Scanning electron microscopes (SEMs) focus a beam of
electrons onto the surface of a specimen, providing images
that look 3-D
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Transmission electron microscopes (TEMs) focus a beam
of electrons through a specimen
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TEMs are used mainly to study the internal structure of cells
Concept 6.2: Eukaryotic cells have internal membranes that
compartmentalize their functions
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The basic structural and functional unit of every organism is
one of two types of cells: prokaryotic or eukaryotic
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Only organisms of the domains Bacteria and Archaea consist
of prokaryotic cells
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Protists, fungi, animals, and plants all consist of eukaryotic
cells
Comparing Prokaryotic and Eukaryotic Cells
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Basic features of all cells:
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Plasma membrane
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Semifluid substance called cytosol
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Chromosomes (carry genes)
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Ribosomes (make proteins)
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Prokaryotic cells are characterized by having
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No nucleus
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DNA in an unbound region called the nucleoid
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No membrane-bound organelles
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Cytoplasm bound by the plasma membrane
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Eukaryotic cells are characterized by having
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DNA in a nucleus that is bounded by a membranous nuclear
envelope
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Membrane-bound organelles
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Cytoplasm in the region between the plasma membrane and
nucleus
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Eukaryotic cells are generally much larger than prokaryotic
cells
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The plasma membrane is a selective barrier that allows
sufficient passage of oxygen, nutrients, and waste to service
the volume of every cell
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The general structure of a biological membrane is a double
layer of phospholipids
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The logistics of carrying out cellular metabolism sets limits on
the size of cells
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The surface area to volume ratio of a cell is critical
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As the surface area increases by a factor of n2, the volume
increases by a factor of n3
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Small cells have a greater surface area relative to volume
A Panoramic View of the Eukaryotic Cell
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A eukaryotic cell has internal membranes that partition the cell
into organelles
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Plant and animal cells have most of the same organelles
Concept 6.3: The eukaryotic cellÕs genetic instructions are housed
in the nucleus and carried out by the ribosomes
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The nucleus contains most of the DNA in a eukaryotic cell
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Ribosomes use the information from the DNA to make proteins
The Nucleus: Information Central
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The nucleus contains most of the cellÕs genes and is usually
the most conspicuous organelle
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The nuclear envelope encloses the nucleus, separating it
from the cytoplasm
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The nuclear membrane is a double membrane; each
membrane consists of a lipid bilayer
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Pores regulate the entry and exit of molecules from the
nucleus
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The shape of the nucleus is maintained by the nuclear
lamina, which is composed of protein
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In the nucleus, DNA and proteins form genetic material called
chromatin
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Chromatin condenses to form discrete chromosomes
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The nucleolus is located within the nucleus and is the site of
ribosomal RNA (rRNA) synthesis
Ribosomes: