Type 2 Diabetes: A Qualitative Study

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The first study was located in Pakistan at an outpatient department of medicine hospital. There were 114 participants for the intervention and 105 participants for the control group. The 114 patients were diagnosed with type 2 diabetes and consuming metformin for at least a year, while the control group were diagnosed with type 2 diabetes but had not taken metformin in the last two years. The participants’ ages ranged from 40 to 70 years old and both genders participated. The study assessed vitamin B-12 levels by blood samples using DXI automated analyzer. They also measured glycosylated hemoglobin through DXC-600 automated analyzer. In addition, the main variables the researchers measured were the amount of metformin consumed, the length of time of being diagnosed with type 2 diabetes, and the length of time of metformin use. Iftikhar and colleagues (2013) found there was a significance with the consumption of metformin. Furthermore, the deficiency in the patients showed another key role in the development was the duration and dose of metformin. The researchers discovered 31% of the prescribed metformin user, were B-12 deficiency, while the control group had about 9% with a B12 deficiency. Iftikhar and the other researchers discovered when the dose of metformin was lower B-12 …show more content…
There was 298 participants and 202 were prescribed and consuming metformin. De Groot-Kamphuis and colleagues (2013) assessed the dosage of metformin, length of time of metformin use, and ***. Blood samples were taken and evaluated with a modular analyzer. They revealed that 14.1% of the participants who took metformin were B-12 deficient compare to 4.4% of the participants did not take metformin. The main variable that was significant was the dosage because for every 100mg increase of metformin, there was a decrease of about 3.77pmol/l (8%) in vitamin B-12

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