Type 1 Diabetes Research Paper

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Diabetes mellitus, the metabolic disorder is rapidly on the rise, becoming one of the main threats to human health and imposing large socio-economic burden on the society in the 21st century (Dall et al.; 2010). According to the International Diabetes Federation, in 2011 over 300 million people around the world have diabetes and is expected to rise to 500 million within next 20 years. The global prevalence of diabetes is changing from the developed countries to the developing countries.
Diabetes mellitus (DM), commonly referred to as diabetes, is a group of metabolic diseases in which there are high blood sugar levels over a prolonged period.[7] Frequent urination, increased thirst, and increased hunger are the common symptoms of high blood …show more content…
This form was previously referred to as "insulin-dependent diabetes mellitus" (IDDM) or "juvenile diabetes".
• Insulin resistance is the main reason for Type 2 DM. It is a condition in which cells fail to respond to insulin properly. Lack of insulin also increases as the disease progress. This form was previously referred to as "non insulin-dependent diabetes mellitus" (NIDDM) or "adult-onset diabetes". The most common cause is excessive body weight and not enough …show more content…
This results from cellular mediated autoimmune destruction of β-cells of the pancreas. So this is also called as insulin-dependent diabetes or juvenile- onset diabetes. Destruction of the β-cell are analysed by certain markers which include islet cell autoantibodies, autoantibodies to insulin, autoantibodies to GAD (GAD65), and autoantibodies to the tyrosine phosphatases IA-2 and IA-2b. These autoantibodies are present when fasting hyperglycemia is detected initially in 85-90% individuals. The rate of β -cell destruction is quite variable in Type 1 diabetes, being rapid in some individuals (mainly infants and children) and slows in others (mainly adults). Some patients, particularly children and adolescents, may present with ketoacidosis as the first manifestation of the disease. At latter stage of the disease, there is little or no insulin secretion, as manifested by low or undetectable levels of plasma C-peptide. Immune-mediated diabetes commonly occurs in childhood and adolescence, but it can occur at any age, even at any time period of

Type 1 Diabetes Research Paper

examples, type 1 and 2 diabetes, gestational diabetes, and prediabetes. The carbohydrates will break down into glucose to carries out through the bloodstream to other organs. The diabetes type 1 and 2 are different, explaining how diet and nutrition affect diabetics and what role does carbohydrates has. Type 1 diabetes was caused by the damaged of the beta pancreas that only to be a mistake. So less glucose is taken into the cells, while the rest of the glucose stayed in the blood. Type 1 diabetes is…

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Type 1 Diabetes Research Paper

Diabetes affects a large percentage of the population, especially in the southern part of America. “Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both” Huether & McCance (2017). There are four classification of diabetes, which are type 1, type 2, gestational, and other specific types. Type 1 diabetes is common in children. It can be either idiopathic or autoimmune. Idiopathic type 1 is caused by…

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Type 1 Diabetes Research Paper

Diabetes People have known about Diabetes for thousands of years, but how did society actually get to a point of understanding what Diabetes really is. One of the earliest ways of diagnosing Diabetes was to physically taste the urine of someone and determine if it tasted sweet, if it did, then diabetes was diagnosed. After many years had gone by, doctors and physicians finally realized that the diet of a person can affect whether one has Diabetes or not. Then, in 1889, the treatment of insulin came…

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Type 1 Diabetes Research Paper

Type 1 Diabetes Every day an approximate 200 children are diagnosed with type 1 diabetes. Type 1 diabetes is a major part of an individual’s life; many diabetics have to deal with the complications of effects and treatments forever. Diabetes is a disease that can ruin a person’s life if it is not treated right. It is caused by a person’s immune system attacking and destroying insulin produced cells in the pancreas (MayoClinic 3). Diabetes is when an insulin hormone called the pancreas does not work…

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Type 1 Diabetes Research Paper

glucose in the blood binds to the glucose receptors. The cell turns the glucose into ATP, a form of energy, so our cells are alive and help us continue our lives. Type 1 diabetes occurs when your body lacks the ability to produce insulin at all. Patients with type 1 diabetes have to take injections with insulin. Type 2 diabetes occurs…

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Type 1 Diabetes Research Paper

Introduction Diabetes is one of the most known long term diseases that has no cure. Diabetes or diabetes mellitus, is a condition where there is too much glucose in the bloodstream. Diabetes mellitus is a long-lasting disorder that affects your body's capability to use the energy found in food. There are three major types of diabetes: type 1 diabetes, type 2 diabetes, and gestational diabetes. All of the types of Diabetes mellitus have something similar about them. A body that is not affected by…

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Type 1 Diabetes Research Paper

Abstract Type 1 diabetes was once known as Juvenile diabetes and insulin dependent diabetes. Joseph Von Mering and Oscar Minkowski found that the pancreas played a major role in diabetes in 1889. They discovered that dogs who had their pancreas removed had symptoms of diabetes and passed away shortly after. About 20 years later, in 1910, Sir Edward Albert Sharper-Schafer found that the cause of diabetes was because of the absence of insulin. There are different symptoms and treatments for different…

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Type 1 Diabetes Research Paper

Diabetes is a metabolic disease characterised by an elevation in serum glucose related to either insulin deficiency or insulin resistance, with gestational diabetes being a special case in which hormonal changes after cellular handling of glucose. It is a very common disease, characterised by an asymptomatic phase between the actual onset of diabetic hyperglycaemia and clinical diagnosis. This phase has been estimated to last at least 4-7 years and 30-50% cases of type-2 diabetic patients remained…

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Type 1 Diabetes Research Paper

How do we educate those with diabetes and help prevent others from being diagnosed? First, we must understand what the disease is and the two types associated with it. Let's define diabetes, so that we are all clear. Diabetes is a disease that is metabolic in nature that is experiencing an upset. The word metabolism speaks to the utilization of food for expansion and vitality. Glucose is the final stage of most delectable bites we place in our mouths. This sweetener is the primary origin of nutrition…

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Type 1 Diabetes Research Paper

Diabetes mellitus is a group of diseases which affects how the body utilizes blood glucose. Blood sugar is important in a person health since it’s a source of energy for the cells that constitute the muscles and tissues. Also, it’s the main source of fuel for the brain. Patients with diabetes no matter the type, have excess, sugar in the blood, though the causes may be different. Elevated blood glucose levels may lead to severe health problems. Chronic diabetes includes type 1 diabetes and type II…

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